Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher.
Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?
Some links on this page may take you to non-federal websites. Their policies may differ from this site.
-
Rapid and accurate detection of the pathogens, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for COVID-19, is critical for mitigating the COVID-19 pandemic. Current state-of-the-art pathogen tests for COVID-19 diagnosis are done in a liquid medium and take 10–30 min for rapid antigen tests and hours to days for polymerase chain reaction (PCR) tests. Herein we report novel accurate pathogen sensors, a new test method, and machine-learning algorithms for a breathalyzer platform for fast detection of SARS-CoV-2 virion particles in the aerosol in 30 s. The pathogen sensors are based on a functionalized molecularly-imprinted polymer, with the template molecules being the receptor binding domain spike proteins for different variants of SARS-CoV-2. Sensors are tested in the air and exposed for 10 s to the aerosols of various types of pathogens, including wild-type, D614G, alpha, delta, and omicron variant SARS-CoV-2, BSA (Bovine serum albumin), Middle East respiratory syndrome–related coronavirus (MERS-CoV), influenza, and wastewater samples from local sewage. Our low-cost, fast-responsive pathogen sensors yield accuracy above 99% with a limit-of-detection (LOD) better than 1 copy/μL for detecting the SARS-CoV-2 virus from the aerosol. The machine-learning algorithm supporting these sensors can accurately detect the pathogens, thereby enabling a new and unique breathalyzer platform for rapid COVID-19 tests with unprecedented speeds.more » « less
-
Most of the next-generation implantable medical devices that are targeting sub-mm scale form factors are entirely powered wirelessly. The most commonly used form of wireless power transfer for ultra-small receivers is inductive coupling and has been so for many decades. This might change with the advent of novel microfabricated magnetoelectric (ME) antennas which are showing great potential as high-frequency wireless powered receivers. In this paper, we compare these two wireless power delivery methods using receivers that operate at 2.52 GHz with a surface area of 0.043 mm2 . Measurement results show that the maximum achievable power transfer of a ME antenna outperforms that of an on-silicon coil by approximately 7 times for a Tx-Rx distance of 2.16 and 3.3 times for a Tx-Rx distance of 0.76 cm.more » « less
An official website of the United States government
